Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | BID | P55957 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.35 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10965484 | 0.76 | GABRA1 (0.37) | HTTTHRB | |
| Tetrabuthylammonium SCHEMBL28838131 | 0.75 | SLC22A1 (0.35) | SLC22A1 | |
| Tetrabuthylammonium SCHEMBL10414184 | 0.72 | HTT (0.47) | HTTCHRM2CYP2D6CHRM1ADRA2C | |
| Tetrabuthylammonium SCHEMBL106854 | 0.72 | TSHR (0.47) | HTTCES2CES1CHRM2OPRK1 | |
| Tetrabuthylammonium SCHEMBL23522678 | 0.71 | LMNA (0.43) | CES2CES1POLBCNR2 | |
| SCHEMBL2964988 | 0.71 | GABRA1 (0.45) | — | |
| Tetrabuthylammonium SCHEMBL10935787 | 0.71 | SLC22A1 (0.36) | HTTCES2CES1BIDMCL1 | |
| Tetrabuthylammonium SCHEMBL9790196 | 0.70 | CNR2 (0.54) | CES2CES1POLBCNR2 | |
| Tetrabuthylammonium SCHEMBL108878 | 0.70 | CA2 (0.55) | CES2CES1CYP2D6SLC22A1CNR2 | |
| Tetrabuthylammonium SCHEMBL23045178 | 0.70 | CA2 (0.55) | CES2CES1CYP2D6SLC22A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477444-B1 | Carbanionic polymerisation initiators | COUNCIL SCIENT IND RES (IN) | 1998-04-08 | — | — | EP | claimed |
| EP-0477444-A1 | Carbanionic polymerisation initiators | Council of Scientific and Industrial Research (IN) | 1992-04-01 | — | — | EP | claimed |