Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611007 | 1.00 | MAPT (0.41) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8304850 | 0.78 | MAPT (0.48) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8304852 | 0.78 | MAPT (0.48) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8308681 | 0.75 | MAPT (0.48) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8308678 | 0.75 | MAPT (0.48) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8303260 | 0.75 | ALDH1A1 (0.42) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8303262 | 0.75 | ALDH1A1 (0.42) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29708126 | 0.74 | MAPT (0.61) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7689039 | 0.74 | MAPT (0.61) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8611009 | 0.73 | POLB (0.42) | MAPTALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814648-A | N-hydroxyureas as antiinflammatory agents | PFIZER INC. (US) | 1998-09-29 | — | — | US | disclosed |