Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | DRD5 | P21918 | 3/20 | 0.49 |
| ▸ | HRH2 | P25021 | 3/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8616693 | 0.89 | HTR2A (0.50) | MAPK1LMNACYP2D6MEN1KMT2A | |
| SCHEMBL7751327 | 0.88 | SLC6A3 (0.54) | MAPK1LMNACYP2D6MEN1KMT2A | |
| SCHEMBL8611835 | 0.87 | DRD3 (0.49) | MAPK1LMNANPSR1CYP2D6MEN1 | |
| Hydrochloric Acid SCHEMBL7544797 | 0.87 | SLC6A3 (0.53) | MAPK1HTTCYP2D6MEN1KMT2A | |
| SCHEMBL7754377 | 0.86 | CYP2D6 (0.48) | MAPK1LMNACYP2D6MEN1KMT2A | |
| SCHEMBL9416450 | 0.83 | CYP2D6 (0.46) | MAPK1LMNACYP2D6MEN1KMT2A | |
| SCHEMBL9143642 | 0.83 | CYP2D6 (0.47) | MAPK1CYP2D6MEN1KMT2ACACNA1F | |
| SCHEMBL8614302 | 0.83 | KCNH2 (0.48) | MAPK1LMNACYP2D6MEN1KMT2A | |
| SCHEMBL8614292 | 0.81 | KCNH2 (0.52) | MAPK1LMNACNR1HTTCYP2D6 | |
| SCHEMBL8610947 | 0.81 | KCNH2 (0.50) | MAPK1LMNACNR1HTTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549796-B1 | DIPHENYLPIPERAZINE DERIVATIVE AND DRUG FOR CIRCULATORY ORGAN CONTAINING THE SAME | POLA CHEM IND INC (JP) | 1998-04-29 | — | — | EP | disclosed |
| US-5391552-A | Has strong antagonism against calcium with less side effects | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1995-02-21 | — | — | US | disclosed |
| EP-0612738-A1 | Diphenylpiperazine derivative and drug for circulatory organ containing the same | POLA CHEMICAL INDUSTRIES, INC. (JP) | 1994-08-31 | — | — | EP | disclosed |
| EP-0549796-A1 | DIPHENYLPIPERAZINE DERIVATIVE AND DRUG FOR CIRCULATORY ORGAN CONTAINING THE SAME | POLA CHEMICAL INDUSTRIES INC (JP) | 1993-07-07 | — | — | EP | disclosed |