Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.50 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.49 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615437 | 0.82 | RAB9A (0.57) | RAB9ASMN1; SMN2MEN1NPC1POLB | |
| SCHEMBL8617206 | 0.80 | RAB9A (0.57) | RAB9ASMN1; SMN2MEN1NPC1POLB | |
| SCHEMBL8616576 | 0.79 | RAB9A (0.57) | RAB9ASMN1; SMN2MEN1NPC1POLB | |
| SCHEMBL8615555 | 0.79 | DGAT1 (0.56) | RAB9ASMN1; SMN2MEN1NPC1POLB | |
| SCHEMBL8650385 | 0.77 | CYP1A2 (0.54) | RAB9ASMN1; SMN2MEN1NPC1POLB | |
| SCHEMBL197017 | 0.76 | LMNA (0.72) | RAB9ASMN1; SMN2MEN1NPC1POLB | |
| SCHEMBL4651399 | 0.76 | RAB9A (0.50) | RAB9ASMN1; SMN2MEN1NPC1KMT2A | |
| SCHEMBL28750517 | 0.76 | KMT2A (1.00) | RAB9ASMN1; SMN2MEN1NPC1POLB | |
| SCHEMBL8616107 | 0.75 | MCL1 (0.60) | RAB9ASMN1; SMN2GAAMCL1GSTP1 | |
| SCHEMBL7665986 | 0.75 | MCL1 (0.60) | RAB9ASMN1; SMN2GAAMCL1GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| EP-0665836-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-08-09 | — | — | EP | disclosed |
| WO-1994010152-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | WO | disclosed |