Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6322177 | 0.87 | SRD5A2 (0.79) | SRD5A2TSHRKDM4ENPC1MAPT | |
| SCHEMBL1651161 | 0.86 | SRD5A2 (0.52) | SRD5A2TSHRLTA4HCES2CES1 | |
| SCHEMBL10398542 | 0.84 | SRD5A2 (0.63) | SRD5A2TSHRKDM4ENPC1MAPT | |
| SCHEMBL257368 | 0.83 | SMN1; SMN2 (0.56) | SRD5A2TSHRLTA4HKDM4ENPC1 | |
| SCHEMBL333237 | 0.82 | SRD5A2 (0.78) | SRD5A2TSHRHSD11B1NPC1RAB9A | |
| SCHEMBL4743809 | 0.82 | SRD5A2 (0.71) | SRD5A2TSHRKDM4ENPC1MAPT | |
| SCHEMBL8436141 | 0.82 | SRD5A2 (1.00) | SRD5A2TSHRVCAM1ALOX15TP53 | |
| SCHEMBL238259 | 0.80 | LTA4H (0.73) | SRD5A2TSHRLTA4HCES2CES1 | |
| SCHEMBL8572071 | 0.80 | LTA4H (0.73) | SRD5A2TSHRLTA4HCES2CES1 | |
| SCHEMBL1736339 | 0.80 | LTA4H (0.73) | SRD5A2TSHRLTA4HCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600318-B1 | Asymmetric, halogenated benzophenones and process for their preparation | CLARIANT GMBH (DE) | 1998-04-08 | — | — | EP | disclosed |
| EP-0600318-A1 | Asymmetric, halogenated benzophenones and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | disclosed |