Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6322177 | 0.89 | SRD5A2 (0.79) | SRD5A2MAPTHTTPKMHPGD | |
| SCHEMBL1758320 | 0.86 | HSD17B1 (0.61) | SRD5A2MAPK1MAPTHTTLMNA | |
| SCHEMBL333237 | 0.83 | SRD5A2 (0.78) | SRD5A2TSHRTDP1L3MBTL1MEN1 | |
| SCHEMBL8436141 | 0.83 | SRD5A2 (1.00) | SRD5A2TSHRVCAM1ALOX15 | |
| SCHEMBL8612482 | 0.82 | SRD5A2 (0.69) | SRD5A2MAPK1MAPTLMNAPKM | |
| SCHEMBL6744294 | 0.82 | SRD5A2 (0.63) | SRD5A2MAPTPKMHPGDTSHR | |
| SCHEMBL11272537 | 0.81 | MAPK1 (0.50) | SRD5A2MAPK1MAPTHTTLMNA | |
| SCHEMBL11639337 | 0.80 | SRD5A2 (0.67) | SRD5A2MAPK1MAPTLMNAPKM | |
| SCHEMBL5685231 | 0.80 | SRD5A2 (0.67) | SRD5A2MAPTHTTPKMHPGD | |
| SCHEMBL699850 | 0.79 | LMNA (1.00) | SRD5A2MAPK1MAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121331-B | Phenoxy aromatic acid compounds with cyclopropyl and pharmaceutically acceptable salts thereof, and preparation methods and applications thereof | 华创合成制药股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| JP-5032776-A | — | — | None | — | — | JP | disclosed |
| WO-2008107320-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES USED AS ANTI-NEOPLASIC AGENTS OR CELL PROLIFERATION INHIBITORS | CEREP (FR) | 2008-09-12 | — | — | WO | disclosed |
| EP-0860433-B1 | QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KIRIN BREWERY (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-6143764-A | ETHER DERIVATIVES OF QUINOLINE, ANTITUMOR AGENTS | KIRIN BEER KABUSHIKI KAISHA (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0860433-A1 | QUINOLINE DERIVATIVES AND QUINAZOLINE DERIVATIVES INHIBITING AUTOPHOSPHORYLATION OF GROWTH FACTOR RECEPTOR ORIGINATING IN PLATELET AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 1998-08-26 | — | — | EP | disclosed |
| JP-H0532776-A | PRODUCTION OF POLYARYL ETHER KETONE | TEIJIN LTD | 1993-02-09 | — | — | JP | disclosed |