Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 10/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10699375 | 0.80 | DGAT1 (0.41) | DGAT1MPOPTGS2TSHRKDM4E | |
| SCHEMBL23565169 | 0.79 | DGAT1 (0.41) | DGAT1MPOALDH1A1MAPTHPGD | |
| SCHEMBL8683781 | 0.79 | ALDH1A1 (0.46) | DGAT1MPOPTGS2KDM4EUSP2 | |
| SCHEMBL25384661 | 0.79 | DGAT1 (0.40) | DGAT1MPOPTGS2TSHRKDM4E | |
| SCHEMBL23565170 | 0.79 | KDM4E (0.44) | DGAT1MPOKDM4EUSP2ALDH1A1 | |
| SCHEMBL4298033 | 0.76 | DGAT1 (0.57) | DGAT1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL14304515 | 0.75 | PTGS2 (0.58) | DGAT1PTGS2KDM4EALDH1A1MAPT | |
| SCHEMBL408273 | 0.75 | DGAT1 (0.54) | DGAT1KDM4EUSP2ALDH1A1MAPT | |
| SCHEMBL12763749 | 0.75 | DGAT1 (0.43) | DGAT1MPOTSHRKDM4EUSP2 | |
| SCHEMBL27722113 | 0.75 | MPO (0.46) | DGAT1MPOKDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750550-A | RESPIRATORY SYSTEM DISORDERS | SANOFI (FR) | 1998-05-12 | — | — | US | disclosed |