SCHEMBL861287

SCHEMBL861287

CC(C)(C)Cc1cc2c(ncc3ccccc32)s1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
GPR3 P46089 1/20 0.39
SMN1; SMN2 Q16637 4/20 0.34
NPC1 O15118 2/20 0.34
HTT P42858 2/20 0.34
RAB9A P51151 2/20 0.34
CCR4 P51679 1/20 0.34
SELE P16581 4/20 0.33
VCAM1 P19320 4/20 0.33
ICAM1 P05362 3/20 0.33
CYP2A6 P11509 2/20 0.33
ALDH1A1 P00352 3/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 2/20 0.33
CYP1A2 P05177 2/20 0.33
MEN1 O00255 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33
MAOA P21397 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL861279 0.69 KDM4E (0.51) KDM4EGPR3SMN1; SMN2NPC1RAB9A
SCHEMBL11893281 0.67 CYP2A6 (0.58) CYP2A6LOXL2
SCHEMBL9851434 0.67 BCL2L1 (0.47) KDM4EGPR3SMN1; SMN2ALDH1A1KMT2A
SCHEMBL20939332 0.66 CYP2A6 (0.33) SELEVCAM1CYP2A6MEN1SLC22A12
SCHEMBL18573476 0.64 CYP1A2 (0.48) SMN1; SMN2NPC1HTTRAB9ACCR4
SCHEMBL3803974 0.63 KDM4E (0.52) KDM4EGPR3SMN1; SMN2HTTRAB9A
SCHEMBL11954970 0.63 CYP11B1 (0.48) CCR4CYP1A2CYP2C9CYP2C19SLC22A12
SCHEMBL16282362 0.62 GABRP (0.41) KDM4EGPR3SMN1; SMN2RAB9AALDH1A1
SCHEMBL26543894 0.62 ALDH1A1 (0.47) KDM4EGPR3SMN1; SMN2NPC1RAB9A
SCHEMBL22396470 0.60 KDM4E (0.44) KDM4EGPR3SMN1; SMN2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
US-8142909-B2 Blue phosphorescent imidazophenanthridine materials UNIVERSAL DISPLAY CORPORATION (US) 2012-03-27 US disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C KDM4E 3612/4885GPR3 1714/4885SMN1; SMN2 4238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.