Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 11/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | CCKBR | P32239 | 3/20 | 0.45 |
| ▸ | CCKAR | P32238 | 2/20 | 0.45 |
| ▸ | AMY2A | P04746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615395 | 0.92 | REN (0.53) | RENCTSK | |
| SCHEMBL8613586 | 0.91 | REN (0.59) | RENCTSKPTPN1CCKBRCCKAR | |
| SCHEMBL8620136 | 0.89 | REN (0.60) | RENCTSKPTPN1 | |
| SCHEMBL8614579 | 0.86 | REN (0.55) | RENCTSKPTPN1 | |
| Hydrochloric Acid SCHEMBL8618101 | 0.85 | OPRM1 (0.47) | REN | |
| SCHEMBL8616116 | 0.83 | REN (0.55) | RENCTSK | |
| SCHEMBL29838892 | 0.81 | CTSK (0.50) | RENCTSKPTPN1 | |
| SCHEMBL8613602 | 0.81 | REN (0.51) | RENCTSK | |
| SCHEMBL8617359 | 0.80 | REN (0.51) | RENCTSK | |
| SCHEMBL29531081 | 0.79 | REN (0.65) | RENCTSKPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |