SCHEMBL8617359

SCHEMBL8617359

CCSCC(NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NC(=O)[C@H](CC(C)C)NCCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
REN P00797 15/20 0.51
CTSS P25774 3/20 0.48
CTSK P43235 2/20 0.48
CTSL P07711 1/20 0.45
CTSB P07858 1/20 0.45
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8616116 0.91 REN (0.55) RENCTSSCTSKCTSLCTSB
SCHEMBL8613586 0.88 REN (0.59) RENCTSSCTSK
SCHEMBL8613602 0.86 REN (0.51) RENCTSSCTSKPPARA
Hydrochloric Acid SCHEMBL8618095 0.85 MMP8 (0.47)
SCHEMBL8615395 0.81 REN (0.53) RENCTSSCTSKCTSLCTSB
SCHEMBL8616604 0.81 CA5A (0.57) RENCTSSCTSKCTSLCTSB
SCHEMBL8620136 0.81 REN (0.60) RENCTSK
SCHEMBL8617115 0.80 REN (0.51) RENCTSSCTSKCTSLCTSB
SCHEMBL8612906 0.80 REN (0.55) RENCTSK
SCHEMBL8614579 0.79 REN (0.55) RENCTSKCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0838471-A1 PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST SAGAMI CHEMICAL RESEARCH CENTER (JP) 1998-04-29 EP disclosed