Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539453 | 0.68 | NFKB1 (0.48) | NFKB1NFKB2RELAALDH1A1TDP1 | |
| SCHEMBL29248756 | 0.65 | AKR1C3 (0.35) | ALDH1A1TDP1 | |
| SCHEMBL2230989 | 0.63 | — | — | |
| SCHEMBL26797744 | 0.60 | ALDH1A1 (0.32) | NFKB1NFKB2RELAALDH1A1MAPK1 | |
| SCHEMBL6288897 | 0.60 | NFKB1 (0.41) | NFKB1NFKB2RELAALDH1A1TDP1 | |
| SCHEMBL2293575 | 0.60 | LMNA (0.34) | ALDH1A1TDP1RECQLHSD17B10 | |
| SCHEMBL24516527 | 0.58 | NFKB1 (0.42) | NFKB1NFKB2RELAALDH1A1TDP1 | |
| SCHEMBL6828416 | 0.57 | BACE1 (0.43) | TDP1NPSR1SMN1; SMN2MAPK1RECQL | |
| SCHEMBL2230292 | 0.57 | MAPT (0.40) | ALDH1A1TDP1NPSR1SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL8504449 | 0.55 | BACE1 (0.42) | TDP1NPSR1SMN1; SMN2MAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129303-B2 | Pathogen-resistant fabrics | LOMBARDI JOHN L (US) | 2012-03-06 | — | — | US | disclosed |
| US-8129303-B2 | Pathogen-resistant fabrics | LOMBARDI JOHN L (US) | 2012-03-06 | — | — | US | disclosed |
| US-20110183572-A1 | Pathogen-Resistant Fabrics | LOMBARDI JOHN L | 2011-07-28 | — | — | US | disclosed |
| US-20110183572-A1 | Pathogen-Resistant Fabrics | LOMBARDI JOHN L | 2011-07-28 | — | — | US | disclosed |