Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.52 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.45 |
| ▸ | CCKBR | P32239 | 4/20 | 0.45 |
| ▸ | CCKAR | P32238 | 3/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620133 | 0.90 | CTSS (0.55) | CTSSCTSKCTSLCTSBCTSD | |
| SCHEMBL8616203 | 0.87 | CTSS (0.47) | PSMB5CTSSCTSKOPRD1CCKBR | |
| SCHEMBL8617778 | 0.85 | CTSS (0.56) | CTSSCTSKCTSLCTSBCTSD | |
| SCHEMBL8614984 | 0.83 | CTSD (0.49) | PSMB8PSMB9PSMB5CTSSCTSK | |
| SCHEMBL8613804 | 0.82 | CTSS (0.50) | CTSSCTSKCTSLCTSBCTSD | |
| SCHEMBL8620934 | 0.81 | CTSD (0.55) | CTSSCTSKCTSLCTSBCTSD | |
| SCHEMBL28799353 | 0.80 | CTSS (0.60) | PSMB8PSMB9PSMB5CTSSCTSK | |
| SCHEMBL28799360 | 0.80 | CTSS (0.60) | PSMB8PSMB9PSMB5CTSSCTSK | |
| SCHEMBL13702233 | 0.78 | ACE (0.59) | PSMB8PSMB9PSMB5CTSSCTSK | |
| SCHEMBL16908988 | 0.78 | ACE (0.59) | PSMB8PSMB9PSMB5CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |