Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 4/20 | 0.55 |
| ▸ | BACE1 | P56817 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614995 | 0.94 | CTSD (0.52) | CTSDBACE1KMT2AMEN1ATM | |
| SCHEMBL8617778 | 0.93 | CTSS (0.56) | CTSDKMT2AATMCTSSCTSL | |
| SCHEMBL8614984 | 0.92 | CTSD (0.49) | CTSDBACE1KMT2AMEN1ATM | |
| SCHEMBL8620133 | 0.89 | CTSS (0.55) | CTSDKMT2AATMCTSSCTSL | |
| SCHEMBL8613804 | 0.87 | CTSS (0.50) | CTSDKMT2AATMCTSSCTSL | |
| SCHEMBL8613599 | 0.85 | CTSD (0.56) | CTSDKMT2AMEN1CTSSCTSL | |
| SCHEMBL8612019 | 0.83 | ANPEP (0.47) | CTSDBACE1KMT2AMEN1ATM | |
| SCHEMBL8613619 | 0.83 | CTSD (0.53) | CTSDKMT2AMEN1CTSSCTSL | |
| SCHEMBL8961019 | 0.82 | ACE (0.60) | CTSDKMT2AMEN1ATMCTSS | |
| SCHEMBL8961015 | 0.82 | ACE (0.60) | CTSDKMT2AMEN1ATMCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |