Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.55 |
| ▸ | CTSK | P43235 | 6/20 | 0.55 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 4/20 | 0.46 |
| ▸ | REN | P00797 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617778 | 0.95 | CTSS (0.56) | CTSSCTSKCTSLCTSBKMT2A | |
| SCHEMBL8613804 | 0.91 | CTSS (0.50) | CTSSCTSKCTSLCTSBKMT2A | |
| SCHEMBL8614984 | 0.91 | CTSD (0.49) | CTSSCTSKCTSLCTSBKMT2A | |
| SCHEMBL8616203 | 0.90 | CTSS (0.47) | CTSSCTSKCTSLCTSBKMT2A | |
| SCHEMBL8613316 | 0.90 | PSMB8 (0.52) | CTSSCTSKCTSLCTSBCTSD | |
| SCHEMBL8620934 | 0.89 | CTSD (0.55) | CTSSCTSKCTSLCTSBKMT2A | |
| SCHEMBL8614995 | 0.85 | CTSD (0.52) | CTSSCTSKCTSLCTSBKMT2A | |
| SCHEMBL8613599 | 0.83 | CTSD (0.56) | CTSSCTSKCTSLCTSBKMT2A | |
| SCHEMBL8612019 | 0.83 | ANPEP (0.47) | CTSSCTSKCTSLCTSBKMT2A | |
| SCHEMBL8619117 | 0.82 | REN (0.49) | KMT2AREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |