Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 4/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 2/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613234 | 0.93 | CDK9 (0.38) | CDK9CCNT1ALDH1A1MEN1KMT2A | |
| SCHEMBL8619171 | 0.89 | MAPT (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8619262 | 0.88 | BACE1 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8620853 | 0.88 | ADORA3 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8614891 | 0.85 | NQO2 (0.34) | MEN1KMT2ASMN1; SMN2POLBMAPT | |
| SCHEMBL8618644 | 0.85 | ADORA3 (0.34) | CDK9CCNT1ALDH1A1MEN1KMT2A | |
| SCHEMBL8617517 | 0.85 | MAPT (0.34) | ALDH1A1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL8615517 | 0.85 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8615844 | 0.84 | ADORA3 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL8616647 | 0.83 | KDM4E (0.38) | PTK2HTTPOLBMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |