Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | CTSA | P10619 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619171 | 0.92 | MAPT (0.39) | ADORA3MAPTADORA1LTB4RALDH1A1 | |
| SCHEMBL8620853 | 0.91 | ADORA3 (0.36) | ADORA3MAPTADORA1LTB4RALDH1A1 | |
| SCHEMBL8617517 | 0.89 | MAPT (0.34) | ADORA3MAPTADORA1LTB4RALDH1A1 | |
| SCHEMBL8614891 | 0.89 | NQO2 (0.34) | ADORA3MAPTADORA1LTB4RMEN1 | |
| SCHEMBL8615517 | 0.89 | ALDH1A1 (0.34) | ADORA3MAPTLTB4RALDH1A1MEN1 | |
| SCHEMBL8615844 | 0.87 | ADORA3 (0.36) | ADORA3MAPTADORA1LTB4RALDH1A1 | |
| SCHEMBL8616647 | 0.86 | KDM4E (0.38) | ADORA3MAPTADORA1HTTKDM4E | |
| SCHEMBL8613368 | 0.85 | CDK9 (0.38) | MAPTALDH1A1CCNT1CDK9MEN1 | |
| SCHEMBL8614898 | 0.85 | NQO2 (0.34) | ADORA3MAPTADORA1LTB4RMEN1 | |
| SCHEMBL8616041 | 0.85 | ALDH1A1 (0.33) | ADORA3MAPTADORA1LTB4RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |