Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618508 | 0.88 | CYP19A1 (0.40) | CYP11B1CYP11B2CYP19A1FEN1MAP4K4 | |
| SCHEMBL8612501 | 0.85 | FEN1 (0.42) | CYP11B1CYP11B2CYP19A1FEN1MAP4K4 | |
| SCHEMBL8613429 | 0.85 | USP28 (0.44) | PTGER1LRRK2RXRARXRBRXRG | |
| SCHEMBL8616654 | 0.83 | USP28 (0.43) | PTGER1LRRK2RXRARXRBRXRG | |
| SCHEMBL8613441 | 0.83 | KDM1A (0.40) | MRGPRX4PTGER1RXRARXRBRXRG | |
| SCHEMBL8615418 | 0.83 | FEN1 (0.50) | CYP11B1CYP11B2CYP19A1FEN1IDO1 | |
| SCHEMBL8614892 | 0.82 | FEN1 (0.43) | CYP11B1CYP11B2CYP19A1FEN1IDO1 | |
| SCHEMBL8617922 | 0.80 | KDM1A (0.40) | FEN1MRGPRX4PTGER1RXRARXRB | |
| SCHEMBL7882570 | 0.80 | MRGPRX4 (0.40) | FEN1IDO1MRGPRX4PTGER1LRRK2 | |
| SCHEMBL8616560 | 0.80 | ERN1 (0.49) | FEN1MAP4K4MRGPRX4PTGER1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |