Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 2/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612967 | 0.90 | GSTP1 (0.55) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL8613296 | 0.89 | GSTP1 (0.52) | GSTP1MCL1LMNACYP1A2PTGS1 | |
| SCHEMBL8614632 | 0.88 | GSTP1 (0.54) | GSTP1MCL1LMNACYP1A2PTGS1 | |
| SCHEMBL8613858 | 0.88 | GSTP1 (0.54) | GSTP1LMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL8616951 | 0.88 | GSTP1 (0.54) | GSTP1MCL1LMNACYP1A2PTGS1 | |
| SCHEMBL8612999 | 0.87 | GSTP1 (0.56) | GSTP1MCL1ARAPPLMNA | |
| SCHEMBL8616115 | 0.87 | GSTP1 (0.56) | GSTP1MCL1ARAPPLMNA | |
| SCHEMBL8613429 | 0.87 | USP28 (0.44) | GSTP1LMNARXRARXRBRAB9A | |
| SCHEMBL10000684 | 0.86 | LMNA (0.69) | GSTP1MCL1APPLMNACYP1A2 | |
| SCHEMBL8615440 | 0.86 | GSTP1 (0.55) | GSTP1MCL1ARAPPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| WO-1994010152-A1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | WO | disclosed |