Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | CETP | P11597 | 2/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619003 | 0.85 | SLC40A1 (0.46) | SLC40A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8613222 | 0.81 | SLC40A1 (0.48) | SLC40A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8613894 | 0.79 | SLC40A1 (0.42) | HDAC3HDAC1HDAC2CETPSLC40A1 | |
| SCHEMBL8615876 | 0.79 | RPS6KB1 (0.38) | SLC40A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8617422 | 0.79 | SLC40A1 (0.38) | SLC40A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8613484 | 0.78 | RAB9A (0.43) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8613492 | 0.78 | ADORA2A (0.44) | SLC40A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8620689 | 0.78 | MEN1 (0.41) | SLC40A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8615118 | 0.78 | SLC40A1 (0.48) | SLC40A1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8616703 | 0.77 | PIK3CA (0.47) | SLC40A1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |