Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588306 | 0.89 | IKBKB (0.40) | UTS2RALDH1A1MAPTPARP1 | |
| SCHEMBL8613696 | 0.81 | HRH3 (0.44) | UTS2RALDH1A1MAPT | |
| SCHEMBL8615064 | 0.78 | ALDH1A1 (0.37) | UTS2RALDH1A1MAPTCHRM2CHRM1 | |
| SCHEMBL8617442 | 0.73 | CHRNB4 (0.46) | — | |
| SCHEMBL8128972 | 0.71 | ALDH1A1 (0.42) | ALDH1A1MAPT | |
| SCHEMBL15880539 | 0.71 | HRH3 (0.47) | PARP1 | |
| SCHEMBL8656325 | 0.71 | ALDH1A1 (0.40) | ALDH1A1MAPT | |
| SCHEMBL17311546 | 0.71 | HRH3 (0.47) | PARP1 | |
| SCHEMBL31641521 | 0.71 | HTR2C (0.54) | UTS2RPOLB | |
| SCHEMBL15880537 | 0.71 | HRH3 (0.47) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |