Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 7/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.36 |
| ▸ | FLT1 | P17948 | 3/20 | 0.36 |
| ▸ | FLT4 | P35916 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 3/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.35 |
| ▸ | TEK | Q02763 | 2/20 | 0.35 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613696 | 0.88 | HRH3 (0.44) | ALDH1A1MAPTMAOAMAOBEGFR | |
| SCHEMBL18152767 | 0.84 | HTR2C (0.40) | ALDH1A1MAPTHTR2AHTR2BHTR2C | |
| SCHEMBL8617442 | 0.82 | CHRNB4 (0.46) | CHRNA4 | |
| SCHEMBL8588306 | 0.81 | IKBKB (0.40) | ALDH1A1MAPTHTR2AHTR2BHTR2C | |
| SCHEMBL8613634 | 0.78 | UTS2R (0.39) | ALDH1A1MAPTUTS2RCHRM2CHRM1 | |
| SCHEMBL8656325 | 0.78 | ALDH1A1 (0.40) | ALDH1A1MAPTHRH3SLC6A4 | |
| SCHEMBL7096511 | 0.73 | HRH3 (0.54) | HRH3HRH1 | |
| SCHEMBL8128972 | 0.73 | ALDH1A1 (0.42) | ALDH1A1MAPT | |
| SCHEMBL18115471 | 0.72 | HTR2C (0.64) | ALDH1A1MAPTHTR2AHTR2BHTR2C | |
| SCHEMBL8612335 | 0.71 | HTR7 (0.44) | ALDH1A1MAPTHTR2AHTR2BHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |