Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 6/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8792100 | 0.86 | CHRNB4 (0.46) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL8613696 | 0.83 | HRH3 (0.44) | — | |
| SCHEMBL8615064 | 0.82 | ALDH1A1 (0.37) | CHRNA4 | |
| SCHEMBL8616789 | 0.74 | SLC6A4 (0.43) | — | |
| SCHEMBL7096511 | 0.73 | HRH3 (0.54) | — | |
| SCHEMBL18152767 | 0.73 | HTR2C (0.40) | — | |
| SCHEMBL8613634 | 0.73 | UTS2R (0.39) | — | |
| SCHEMBL8588306 | 0.73 | IKBKB (0.40) | — | |
| SCHEMBL8795585 | 0.72 | SLC6A4 (0.42) | CHRNB4CHRNA3 | |
| SCHEMBL1928412 | 0.71 | CHRNB4 (0.72) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |