Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613871 | 0.88 | CYP11B1 (0.41) | CYP19A1CYP11B1CYP11B2FEN1KDM1A | |
| SCHEMBL8614892 | 0.86 | FEN1 (0.43) | CYP19A1CYP11B1CYP11B2FEN1KDM1A | |
| SCHEMBL8613429 | 0.83 | USP28 (0.44) | KDM1APTGER1LRRK2RAB9A | |
| SCHEMBL8616654 | 0.82 | USP28 (0.43) | KDM1APTGER1LRRK2RAB9A | |
| SCHEMBL8613441 | 0.82 | KDM1A (0.40) | KDM1AMRGPRX4PTGER1MAPTMAPK1 | |
| SCHEMBL8612501 | 0.81 | FEN1 (0.42) | CYP19A1CYP11B1CYP11B2FEN1KDM1A | |
| SCHEMBL7882570 | 0.81 | MRGPRX4 (0.40) | FEN1KDM1AMAPK14ALOX5APIDO1 | |
| SCHEMBL8613438 | 0.80 | KDM1A (0.43) | KDM1AMRGPRX4MAPTMAPK1TDP1 | |
| SCHEMBL8619299 | 0.80 | KDM1A (0.43) | KDM1AMRGPRX4MAPTMAPK1TDP1 | |
| SCHEMBL24896625 | 0.80 | AKT1 (0.42) | CYP19A1CYP11B1CYP11B2FEN1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665836-B1 | BIFUNCTIONAL INTERMEDIATES FOR USE IN THE MANUFACTURE OF LIQUID CRYSTALS | HOECHST AG (DE) | 1998-04-29 | — | — | EP | disclosed |