Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 8/20 | 0.45 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
| ▸ | TRHDE | Q9UKU6 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8614625 | 0.84 | CPB2 (0.43) | TRHDE | |
| SCHEMBL17642069 | 0.82 | ACE (0.56) | CTSSCTSKCTSLCTSBAKT1 | |
| SCHEMBL3429311 | 0.82 | ACE (0.56) | CTSSCTSKCTSLCTSBAKT1 | |
| Hydrochloric Acid SCHEMBL8613807 | 0.82 | MMP3 (0.41) | RENTRHDE | |
| SCHEMBL30064788 | 0.82 | CTSS (0.47) | RENCTSSCTSKCTSLCTSB | |
| SCHEMBL19508750 | 0.81 | KLK5 (0.51) | CTSSCTSKCTSLCTSBAKT1 | |
| SCHEMBL5358340 | 0.79 | MAPT (0.46) | CTSSCTSKCTSLCTSBMAPK1 | |
| SCHEMBL8121405 | 0.78 | CTSS (0.52) | CTSSCTSKCTSLCTSBAKT1 | |
| SCHEMBL8121406 | 0.78 | CTSS (0.52) | CTSSCTSKCTSLCTSBAKT1 | |
| SCHEMBL8615395 | 0.78 | REN (0.53) | RENCTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |