Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2322069 | 0.81 | ALDH1A1 (0.46) | LMNAMAPTALOX15NFKB1SMN1; SMN2 | |
| SCHEMBL30422061 | 0.81 | ALDH1A1 (0.46) | LMNAMAPTALOX15NFKB1SMN1; SMN2 | |
| SCHEMBL8611379 | 0.78 | HSP90AA1 (0.37) | LMNAMAPTTP53ALOX15MAPK1 | |
| Dimethylamine SCHEMBL8610644 | 0.75 | HSD17B10 (0.41) | LMNAMAPTMAPK1SMN1; SMN2MEN1 | |
| SCHEMBL13092724 | 0.73 | MAPT (0.59) | LMNAMAPTTP53ALOX15MAPK1 | |
| SCHEMBL29636933 | 0.73 | MAPT (0.59) | LMNAMAPTTP53ALOX15MAPK1 | |
| SCHEMBL8611019 | 0.73 | HSD17B10 (0.41) | LMNATP53ALOX15MAPK1KDM4E | |
| SCHEMBL1452106 | 0.72 | ACHE (0.46) | MAPK1NPC1ESR2 | |
| SCHEMBL30274610 | 0.72 | ACHE (0.46) | MAPK1NPC1ESR2 | |
| SCHEMBL8436471 | 0.72 | ACHE (0.35) | LMNAMAPTALOX15MAPK1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| EP-0748811-A1 | Process for the preparation of hydroxybiarylphosphanes and novel compounds from this materials group | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-18 | — | — | EP | disclosed |