Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.67 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.62 |
| ▸ | PTPRB | P23467 | 1/20 | 0.57 |
| ▸ | CDC25A | P30304 | 1/20 | 0.57 |
| ▸ | CDC25B | P30305 | 1/20 | 0.57 |
| ▸ | PTEN | P60484 | 1/20 | 0.57 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70271 | 0.90 | KEAP1 (0.74) | KEAP1FFAR1PTPRBCDC25ACDC25B | |
| SCHEMBL11981977 | 0.89 | KEAP1 (0.61) | KEAP1FFAR1PTPRBCDC25ACDC25B | |
| SCHEMBL8435278 | 0.88 | FFAR1 (0.80) | KEAP1FFAR1PTPRBCDC25ACDC25B | |
| Hydrochloric Acid SCHEMBL10982620 | 0.88 | KEAP1 (0.71) | KEAP1FFAR1PTPRBCDC25ACDC25B | |
| SCHEMBL9051375 | 0.82 | FFAR1 (0.64) | KEAP1FFAR1PTPRBCDC25ACDC25B | |
| SCHEMBL30638471 | 0.82 | KEAP1 (0.63) | KEAP1FFAR1PTPRBCDC25ACDC25B | |
| SCHEMBL4407150 | 0.82 | KEAP1 (0.63) | KEAP1FFAR1PTPRBCDC25ACDC25B | |
| Phenyl Propionic Acid SCHEMBL6660445 | 0.81 | KEAP1 (0.68) | KEAP1FFAR1PTPRBCDC25ACDC25B | |
| Phenyl Propionic Acid SCHEMBL13618844 | 0.81 | KEAP1 (1.00) | KEAP1FFAR1ALDH1A1HDAC3MAPK1 | |
| Phenyl Propionic Acid SCHEMBL3419 | 0.81 | KEAP1 (1.00) | KEAP1FFAR1ALDH1A1HDAC3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736285-A | PHOTOSENSITIVE LAYER CONTAINS CHARGE TRANSPORTING POLYESTER AND ATLEAST ONE BISAZO PIGMENT; WEAR RESISTANCE AND ELECTRIC STABILITY | FUJI XEROX CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |