Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618670 | 0.89 | PTGS1 (0.42) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL8622010 | 0.86 | LTA4H (0.47) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL8615041 | 0.85 | LMNA (0.38) | SRD5A2ALDH1A1GAALMNA | |
| SCHEMBL8615047 | 0.85 | LMNA (0.38) | SRD5A2ALDH1A1GAALMNA | |
| SCHEMBL8617483 | 0.79 | LTA4H (0.38) | MEN1KMT2AALDH1A1MAPTTP53 | |
| SCHEMBL8619898 | 0.77 | PTGER4 (0.37) | SRD5A2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19807299 | 0.68 | PTGS1 (0.50) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL11841474 | 0.67 | PTGS1 (0.80) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL5304020 | 0.66 | PTGS1 (0.47) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL11276699 | 0.66 | PTGS1 (0.51) | PTGS1MEN1CYP2D6KMT2AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710102-A | Difluorovinylsilane insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-01-20 | — | — | US | disclosed |