SCHEMBL8619898

SCHEMBL8619898

C[SiH](C)C(C(F)=C(F)c1ccc(Cl)cc1)c1ccc(F)c(Oc2ccccc2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 4/20 0.37
PTGER2 P43116 2/20 0.37
LMNA P02545 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.35
UTS2R Q9UKP6 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
SRD5A2 P31213 1/20 0.33
KCNQ3 O43525 1/20 0.32
KCNQ2 O43526 1/20 0.32
KCNE1 P15382 1/20 0.32
KCNQ1 P51787 1/20 0.32
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
PARP10 Q53GL7 1/20 0.32
DUT P33316 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8615041 0.92 LMNA (0.38) PTGER4PTGER2LMNAL3MBTL1SMN1; SMN2
SCHEMBL8615047 0.92 LMNA (0.38) PTGER4PTGER2LMNAL3MBTL1SMN1; SMN2
SCHEMBL8615546 0.87 LTA4H (0.40) LMNAL3MBTL1LPAR1LPAR5
SCHEMBL8618670 0.85 PTGS1 (0.42) PTGER4PTGER2UTS2RSRD5A2PPARG
SCHEMBL8614960 0.77 PTGS1 (0.43) LMNANPSR1CYP1A2CYP3A4CYP2C9
SCHEMBL8617483 0.75 LTA4H (0.38) LMNAL3MBTL1PPARGPPARA
SCHEMBL8622010 0.71 LTA4H (0.47) LMNAL3MBTL1SRD5A2
SCHEMBL10561616 0.70 LMNA (0.49) LMNADUT
SCHEMBL9540375 0.70 UGT2B7 (0.47) LMNAL3MBTL1SRD5A2KCNQ3KCNQ2
SCHEMBL10549937 0.70 UGT2B7 (0.47) LMNAL3MBTL1SRD5A2KCNQ3KCNQ2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5710102-A Difluorovinylsilane insecticidal and acaricidal agents AMERICAN CYANAMID COMPANY (US) 1998-01-20 US disclosed