Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | TTPA | P49638 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620604 | 0.86 | KMT2A (0.50) | PPARGKMT2AMAPTMEN1TDP1 | |
| SCHEMBL8619591 | 0.83 | PPARG (0.50) | PPARGKMT2AMAPTMEN1TDP1 | |
| SCHEMBL8619652 | 0.82 | MEN1 (0.49) | PPARGKMT2AMAPTMEN1TDP1 | |
| SCHEMBL8619704 | 0.78 | MAPT (0.57) | PPARGKMT2AMAPTMEN1TDP1 | |
| SCHEMBL8003203 | 0.77 | MAPT (0.64) | PPARGKMT2AMAPTMEN1TDP1 | |
| SCHEMBL8615056 | 0.74 | MAPT (0.48) | PPARGKMT2AMAPTMEN1TDP1 | |
| SCHEMBL7986932 | 0.74 | MAPT (0.61) | PPARGKMT2AMAPTMEN1TDP1 | |
| SCHEMBL7492850 | 0.72 | MAPT (0.59) | PPARGKMT2AMAPTMEN1TDP1 | |
| SCHEMBL8620610 | 0.72 | PPARG (0.49) | PPARGKMT2AMAPTMEN1TDP1 | |
| SCHEMBL9632107 | 0.71 | MAPT (0.60) | PPARGKMT2AMAPTMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747528-A | Chroman derivatives as anti-oxidants | WARNER-LAMBERT COMPANY (US) | 1998-05-05 | — | — | US | claimed |