Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL856677 | 0.67 | LMNA (0.39) | GAAMAPTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL5738210 | 0.67 | ADORA2A (0.32) | — | |
| SCHEMBL14592445 | 0.66 | MAPT (0.66) | GAAMAPTRAB9ASMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL856678 | 0.66 | LMNA (0.38) | GAAMAPTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL855359 | 0.66 | GAA (0.38) | GAAMAPTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6956027 | 0.65 | HSD17B10 (0.48) | GAAMAPTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL10896790 | 0.65 | L3MBTL1 (0.39) | GAAMAPTRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6821893 | 0.64 | ALDH1A1 (0.37) | MAPTSMN1; SMN2KMT2ACYP1A2CYP2D6 | |
| SCHEMBL3827052 | 0.64 | KCNN4 (0.33) | GAAMAPTKMT2ATSHR | |
| SCHEMBL5240366 | 0.64 | KCNN4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225209-B1 | PROCESS FOR THE PREPARATION OF 5-(2-ETHYL-DIHYDRO-1H-INDEN-2-YL)-1H-IMIDAZOLE AND SALTS THEREOF | GRINDEKS JSC (LV) | 2012-03-28 | — | — | EP | claimed |