Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6171944 | 0.70 | LMNA (0.36) | TRPA1 | |
| SCHEMBL6173883 | 0.69 | TRPA1 (0.39) | TRPA1 | |
| SCHEMBL15320562 | 0.68 | CA1 (0.38) | TRPA1 | |
| SCHEMBL27529392 | 0.68 | MEN1 (0.33) | TRPA1 | |
| Hydrochloric Acid SCHEMBL15322807 | 0.67 | CA1 (0.37) | TRPA1 | |
| SCHEMBL4748281 | 0.66 | TRPA1 (0.34) | TRPA1 | |
| SCHEMBL444400 | 0.62 | TRPA1 (0.34) | TRPA1 | |
| Urea SCHEMBL8887503 | 0.60 | TRPA1 (0.40) | TRPA1 | |
| SCHEMBL11830486 | 0.60 | TRPA1 (0.35) | TRPA1 | |
| SCHEMBL29757278 | 0.58 | KDM4E (0.36) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432779-A1 | BENZOXAZEPINES BASED P13K/MT0R INHIBITORS AGAINST PROLIFERATIVE DISEASES | Exelixis, Inc. (US) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010135524-A1 | BENZOXAZEPINES BASED P13K/MT0R INHIBITORS AGAINST PROLIFERATIVE DISEASES | EXELIXIS, INC. (US) | 2010-11-25 | — | — | WO | disclosed |