Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SCN4A | P35499 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268163 | 0.93 | TRPA1 (0.38) | TRPA1ATMIKBKB | |
| SCHEMBL11830486 | 0.90 | TRPA1 (0.35) | TRPA1ATMMAPK1HSP90AA1 | |
| SCHEMBL5944362 | 0.73 | ALDH1A1 (0.44) | TRPA1LMNATSHR | |
| Urea SCHEMBL8887498 | 0.72 | KDM4E (0.35) | TRPA1ATMLMNATSHRMAPK1 | |
| SCHEMBL8804196 | 0.72 | TRPA1 (0.36) | TRPA1KEAP1 | |
| SCHEMBL6173883 | 0.71 | TRPA1 (0.39) | TRPA1ATMLMNATSHR | |
| SCHEMBL10483802 | 0.69 | MYC (0.42) | LMNATSHR | |
| SCHEMBL4748281 | 0.68 | TRPA1 (0.34) | TRPA1ATM | |
| SCHEMBL19859170 | 0.68 | KEAP1 (0.33) | TRPA1ATMKEAP1NFE2L2BCAT2 | |
| SCHEMBL9268154 | 0.67 | KDM4E (0.33) | TRPA1ATMLMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661146-A | ANALGESICS | G.D. SEARLE & CO. (US) | 1997-08-26 | — | — | US | disclosed |