Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | CTSK | P43235 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618823 | 0.89 | CTSS (0.43) | CTSSCTSKPPARAPPARGATM | |
| SCHEMBL17395943 | 0.87 | CTSS (0.49) | CTSSCTSKPPARAPPARGATM | |
| SCHEMBL21777294 | 0.87 | CTSS (0.49) | CTSSCTSKPPARAPPARGATM | |
| SCHEMBL265969 | 0.87 | CTSS (0.49) | CTSSCTSKPPARAPPARGATM | |
| SCHEMBL8622411 | 0.86 | CTSK (0.48) | CTSSCTSKATMCTSLCTSB | |
| SCHEMBL8618842 | 0.85 | CTSS (0.41) | CTSSCTSKPPARAPPARGATM | |
| SCHEMBL8622009 | 0.83 | CTSS (0.39) | CTSSCTSKPPARAPPARGATM | |
| SCHEMBL21777285 | 0.83 | PPARG (0.53) | CTSSCTSKPPARAPPARGACE | |
| SCHEMBL8615780 | 0.82 | CTSK (0.39) | CTSSCTSKATMACECTSL | |
| SCHEMBL8619927 | 0.80 | PPARG (0.44) | CTSSCTSKPPARAPPARGATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839799-A1 | 2-HYDROXYPHENYLALKYLAMINE DERIVATIVES AND MAILLARD REACTION INHIBITORS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-05-06 | — | — | EP | disclosed |