Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 5/20 | 0.38 |
| ▸ | CTSS | P25774 | 5/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615780 | 0.91 | CTSK (0.39) | MAPTCTSKCTSSATMACE | |
| SCHEMBL8622009 | 0.87 | CTSS (0.39) | PPARGMAPTALDH1A1LMNATP53 | |
| SCHEMBL8615645 | 0.80 | CTSS (0.46) | PPARGMAPTPPARACTSKCTSS | |
| SCHEMBL8618823 | 0.79 | CTSS (0.43) | PPARGMAPTTP53PPARACTSK | |
| SCHEMBL3447780 | 0.78 | CACNA1B (0.47) | MAPTALDH1A1LMNATP53PKM | |
| SCHEMBL14044925 | 0.78 | CTSK (0.46) | CTSKCTSSCACNA1BATM | |
| SCHEMBL10217306 | 0.78 | CTSK (0.46) | CTSKCTSSCACNA1BATM | |
| SCHEMBL4712952 | 0.78 | CTSK (0.51) | MAPTALDH1A1LMNATP53PKM | |
| SCHEMBL6185014 | 0.78 | CTSK (0.51) | MAPTALDH1A1LMNATP53PKM | |
| SCHEMBL27488331 | 0.78 | CTSK (0.51) | MAPTALDH1A1LMNATP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839799-A1 | 2-HYDROXYPHENYLALKYLAMINE DERIVATIVES AND MAILLARD REACTION INHIBITORS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-05-06 | — | — | EP | disclosed |