Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1738732 | 0.89 | CTSS (0.45) | CTSSCTSKATMCTSLCTSB | |
| SCHEMBL29582289 | 0.89 | CTSS (0.45) | CTSSCTSKATMCTSLCTSB | |
| SCHEMBL14044920 | 0.89 | CTSS (0.45) | CTSSCTSKATMCTSLCTSB | |
| SCHEMBL8615780 | 0.87 | CTSK (0.39) | CTSSCTSKATMCTSLCTSB | |
| SCHEMBL8619927 | 0.87 | PPARG (0.44) | CTSSCTSKATMCTSLCTSB | |
| SCHEMBL8615645 | 0.83 | CTSS (0.46) | CTSSCTSKATMCTSLCTSB | |
| SCHEMBL8618823 | 0.82 | CTSS (0.43) | CTSSCTSKATMCTSLCTSB | |
| SCHEMBL28080125 | 0.81 | ALOX12 (0.40) | CTSSCTSKATMCTSLCTSB | |
| SCHEMBL29747547 | 0.79 | JAK2 (0.43) | CTSSCTSKATMCTSLCTSB | |
| SCHEMBL10270101 | 0.79 | JAK2 (0.43) | CTSSCTSKATMCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839799-A1 | 2-HYDROXYPHENYLALKYLAMINE DERIVATIVES AND MAILLARD REACTION INHIBITORS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-05-06 | — | — | EP | disclosed |