SCHEMBL8616029

SCHEMBL8616029

CCOC(=O)CCc1cccc(Nc2ccc(C)c(C)c2)c1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SYK P43405 5/20 0.50
SIRT2 Q8IXJ6 1/20 0.48
CYP4F2 P78329 2/20 0.47
CYP4A11 Q02928 2/20 0.47
MAPT P10636 3/20 0.45
LMNA P02545 1/20 0.45
MAPK1 P28482 1/20 0.45
HSD17B10 Q99714 1/20 0.45
DHODH Q02127 3/20 0.44
ALDH1A1 P00352 1/20 0.44
HTT P42858 1/20 0.44
MTNR1B P49286 1/20 0.43
EGFR P00533 1/20 0.42
ERBB3 P21860 1/20 0.42
CYP4Z1 Q86W10 1/20 0.41
BRD4 O60885 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30967793 0.82 CYP4F2 (0.53) SYKSIRT2CYP4F2CYP4A11MAPT
SCHEMBL2082531 0.81 CYP4F2 (0.51) SYKSIRT2CYP4F2CYP4A11MAPT
SCHEMBL13865269 0.81 CYP4F2 (0.51) SYKSIRT2CYP4F2CYP4A11MAPT
SCHEMBL4425984 0.80 CYP4F2 (0.64) SYKCYP4F2CYP4A11ALDH1A1CYP4Z1
SCHEMBL16316705 0.79 CYP4F2 (0.49) SYKSIRT2CYP4F2CYP4A11MAPT
SCHEMBL8055023 0.77 CYP4F2 (0.47) SYKCYP4F2CYP4A11ALDH1A1CYP4Z1
SCHEMBL6289443 0.77 SMN1; SMN2 (0.49) SIRT2CYP4F2CYP4A11MAPTLMNA
SCHEMBL879289 0.76 CYP4F2 (0.58) SYKCYP4F2CYP4A11CYP4Z1
SCHEMBL13104077 0.76 CYP4F2 (0.58) SYKCYP4F2CYP4A11MAPTMAPK1
SCHEMBL1816399 0.76 SYK (0.52) SYKSIRT2CYP4F2CYP4A11MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5736285-A PHOTOSENSITIVE LAYER CONTAINS CHARGE TRANSPORTING POLYESTER AND ATLEAST ONE BISAZO PIGMENT; WEAR RESISTANCE AND ELECTRIC STABILITY FUJI XEROX CO., LTD. (JP) 1998-04-07 US disclosed
US-5731118-A Charge transporting random copolyester resin, process for producing the same and organic electronic device using the same FUJI XEROX CO., LTD. (JP) 1998-03-24 US disclosed
US-5677097-A STABILITY, DURABILITY FUJI XEROX CO., LTD. (JP) 1997-10-14 US disclosed