Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30958574 | 0.78 | ALDH1A1 (0.47) | BCL2ALDH1A1MAPTPKMHPGD | |
| SCHEMBL14886257 | 0.74 | NISCH (0.61) | CSNK1A1TYRO3DYRK1BMTORADK | |
| SCHEMBL8537576 | 0.73 | CSNK1A1 (0.49) | CSNK1A1TYRO3DYRK1BMTORADK | |
| Hydrochloric Acid SCHEMBL20204146 | 0.72 | CSNK1A1 (0.47) | CSNK1A1TYRO3DYRK1BMTORADK | |
| SCHEMBL20495594 | 0.72 | MAOA (0.44) | BCL2ALDH1A1MAPTPKMHPGD | |
| SCHEMBL30548748 | 0.72 | MAOA (0.44) | BCL2ALDH1A1MAPTPKMHPGD | |
| SCHEMBL9287236 | 0.72 | NISCH (0.64) | CSNK1A1TYRO3DYRK1BMTORADK | |
| SCHEMBL29242084 | 0.72 | ALDH1A1 (0.42) | BCL2ALDH1A1MAPTPKMHPGD | |
| SCHEMBL8538412 | 0.71 | PDE5A (0.57) | CSNK1A1TYRO3DYRK1BMTORADK | |
| SCHEMBL8536874 | 0.70 | CSNK1A1 (0.45) | CSNK1A1TYRO3DYRK1BMTORADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0857171-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-08-12 | — | — | EP | disclosed |
| WO-1997015555-A2 | IMIDAZOLE DERIVATIVES AND THE USE THEREOF AS NITROGEN MONOXIDE SYNTHASE INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-01 | — | — | WO | disclosed |