Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617724 | 0.87 | ABCG2 (0.41) | ABCB1ABCC1ABCG2ACP1CYP3A4 | |
| SCHEMBL8613362 | 0.86 | ACHE (0.41) | ABCB1ABCC1ABCG2ACP1CYP3A4 | |
| SCHEMBL8618937 | 0.86 | PTGER4 (0.46) | ABCB1ABCC1ABCG2TRPV1ACP1 | |
| SCHEMBL8616598 | 0.86 | ABCG2 (0.40) | ABCB1ABCC1ABCG2TRPV1ACP1 | |
| SCHEMBL8613690 | 0.85 | ELANE (0.42) | ACP1CYP3A4MEN1KMT2AMAPT | |
| SCHEMBL8615866 | 0.84 | ABCB1 (0.39) | ABCB1ABCC1ABCG2ACP1MEN1 | |
| SCHEMBL8614064 | 0.84 | ABCB1 (0.50) | ABCB1ABCC1ABCG2ACP1MEN1 | |
| SCHEMBL8620632 | 0.84 | HPGD (0.44) | ABCB1ABCC1ABCG2TRPV1ACP1 | |
| SCHEMBL8617753 | 0.83 | ACP1 (0.51) | ABCB1ABCC1ABCG2ACP1CYP3A4 | |
| SCHEMBL8620896 | 0.83 | MEN1 (0.41) | ABCB1ABCC1ABCG2ACP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |