Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25727921 | 0.79 | LOXL2 (0.45) | PTGES2GAAASIC3MAPTL3MBTL1 | |
| SCHEMBL12391039 | 0.78 | ASIC3 (0.50) | PTGES2GAAASIC3MAPTL3MBTL1 | |
| SCHEMBL13849645 | 0.77 | CYP2A6 (0.47) | PTGES2GAAASIC3MAPTL3MBTL1 | |
| SCHEMBL8978722 | 0.74 | PTGES2 (0.47) | PTGES2GAAASIC3MAPTL3MBTL1 | |
| SCHEMBL8616508 | 0.74 | LOXL2 (0.48) | L3MBTL1ALDH1A1HTTTSHR | |
| SCHEMBL25727924 | 0.72 | LOXL2 (0.53) | PTGES2GAAASIC3MAPTL3MBTL1 | |
| SCHEMBL3448180 | 0.72 | APP (0.54) | PTGES2ASIC3MAPTL3MBTL1HTT | |
| SCHEMBL8978928 | 0.71 | PTGES2 (0.45) | PTGES2MAPTALDH1A1LMNATSHR | |
| SCHEMBL7873499 | 0.71 | MAPT (0.44) | PTGES2GAAASIC3MAPTL3MBTL1 | |
| SCHEMBL8623109 | 0.71 | CA12 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648723-B1 | Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same | SUMITOMO CHEMICAL CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5658489-A | EXCELLENT ANISOTROPY OF REFRACTIVE INDEX; LOW VISCOSITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0648723-A1 | Diphenylacetylene compound, process for preparing the same and liquid crystal composition and element comprising the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-04-19 | — | — | EP | disclosed |