Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 5/20 | 0.53 |
| ▸ | CASP7 | P55210 | 2/20 | 0.53 |
| ▸ | CASP1 | P29466 | 4/20 | 0.52 |
| ▸ | CASP9 | P55211 | 3/20 | 0.52 |
| ▸ | CTSB | P07858 | 5/20 | 0.49 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | CASP4 | P49662 | 1/20 | 0.47 |
| ▸ | CASP5 | P51878 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.47 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613317 | 0.94 | CTSB (0.49) | CASP3CASP7CASP1CASP9CTSB | |
| SCHEMBL8613765 | 0.90 | CTSB (0.51) | CASP3CASP7CASP1CASP9CTSB | |
| SCHEMBL8613599 | 0.88 | CTSD (0.56) | CASP3CASP7CASP1CASP9CTSB | |
| SCHEMBL8619113 | 0.87 | CTSB (0.48) | CASP3CASP7CASP1CASP9CTSB | |
| SCHEMBL8613619 | 0.85 | CTSD (0.53) | CASP3CASP7CASP1CASP9CTSB | |
| SCHEMBL8613805 | 0.85 | CTSB (0.51) | CASP3CASP7CASP1CASP9CTSB | |
| SCHEMBL8614987 | 0.84 | CA2 (0.57) | CASP3CASP7CASP1CASP9CTSB | |
| SCHEMBL8614145 | 0.83 | CTSB (0.60) | CASP3CASP7CASP1CASP9CTSB | |
| SCHEMBL8614143 | 0.83 | CTSB (0.60) | CASP3CASP7CASP1CASP9CTSB | |
| Hydrochloric Acid SCHEMBL8612178 | 0.83 | CTSD (0.51) | CASP3CASP7CASP1CASP9CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |