Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 2/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | CTSD | P07339 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CASP9 | P55211 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613004 | 0.95 | CASP3 (0.55) | CA2CA5ACASP3CASP7CTSD | |
| SCHEMBL8613765 | 0.94 | CTSB (0.51) | CA2CA5ACASP3CASP7CTSD | |
| SCHEMBL8615292 | 0.92 | REN (0.57) | CA2CA5ACASP3CASP7CASP1 | |
| SCHEMBL8619113 | 0.90 | CTSB (0.48) | CA2CA5ACASP3CASP7CTSD | |
| SCHEMBL8617212 | 0.89 | CASP3 (0.53) | CA2CA5ACASP3CASP7CTSD | |
| SCHEMBL8613599 | 0.85 | CTSD (0.56) | CASP3CASP7CTSDCASP1CASP9 | |
| SCHEMBL8613317 | 0.85 | CTSB (0.49) | CASP3CASP7CTSDCASP1CASP9 | |
| SCHEMBL28252140 | 0.85 | ECE1 (0.64) | CASP3CASP7CTSDCASP1CASP9 | |
| SCHEMBL8612642 | 0.85 | ECE1 (0.64) | CASP3CASP7CTSDCASP1CASP9 | |
| SCHEMBL8616604 | 0.85 | CA5A (0.57) | CA5ARENCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0838471-A1 | PEPTIDE DERIVATIVES AND ANGIOTENSIN IV RECEPTOR AGONIST | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1998-04-29 | — | — | EP | disclosed |