Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | LTA4H | P09960 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535486 | 0.92 | — | — | |
| SCHEMBL9242729 | 0.86 | MAOA (0.74) | MAOAMAOBLTA4HLMNACYP2A6 | |
| SCHEMBL457634 | 0.86 | MAOA (0.74) | MAOAMAOBLTA4HLMNACYP2A6 | |
| Formaldehyde SCHEMBL28347928 | 0.83 | MAOA (0.64) | MAOAMAOBLTA4HLMNACYP2A6 | |
| SCHEMBL30385926 | 0.83 | MAOA (0.70) | MAOAMAOBLTA4HLMNACYP2A6 | |
| SCHEMBL3746973 | 0.83 | ALDH1A1 (0.50) | MAOAMAOBLMNAALDH1A1KDM4E | |
| SCHEMBL2092129 | 0.79 | MAOA (0.58) | MAOAMAOBLTA4HLMNACYP2A6 | |
| SCHEMBL9121691 | 0.78 | MAOA (0.64) | MAOAMAOBLTA4HLMNACYP2A6 | |
| SCHEMBL28983374 | 0.76 | LTA4H (0.67) | MAOAMAOBLTA4HMEN1KMT2A | |
| SCHEMBL2095654 | 0.76 | LTA4H (0.67) | MAOAMAOBLTA4HMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023128696-A1 | NOVEL METHOD FOR PREPARING SUBSTITUTED 1-HYDROXY-2-PYRIDONE COMPOUND | 주식회사 케이씨아이 | 2023-07-06 | — | — | WO | claimed |
| US-20130203822-A1 | COMPOUNDS FOR TREATMENT OF TUMORS BEARING DEREGULATED MYC ONCOPROTEINS | QUATTRONE ALESSANDRO (IT) | 2013-08-08 | — | — | US | claimed |
| EP-2590648-A2 | COMPOUNDS FOR TREATMENT OF TUMORS BEARING DEREGULATED MYC ONCOPROTEINS | Quattrone, Alessandro (IT) | 2013-05-15 | — | — | EP | claimed |
| WO-2011161631-A2 | COMPOUNDS FOR TREATMENT OF TUMORS BEARING DEREGULATED MYC ONCOPROTEINS | QUATTRONE ALESSANDRO (IT) | 2011-12-29 | — | — | WO | claimed |
| US-5817825-A | Process for the preparation of 1-hydroxy-2-pyridones | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-10-06 | — | — | US | claimed |
| EP-0710650-B1 | Process for the preparation of 1-hydroxy-2-pyridones | HOECHST AG (DE) | 1998-08-26 | — | — | EP | claimed |
| EP-0710650-A2 | Process for the preparation of 1-hydroxy-2-pyridones | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-08 | — | — | EP | claimed |
| WO-2023128696-A1 | NOVEL METHOD FOR PREPARING SUBSTITUTED 1-HYDROXY-2-PYRIDONE COMPOUND | 주식회사 케이씨아이 | 2023-07-06 | — | — | WO | disclosed |
| US-5817825-A | Process for the preparation of 1-hydroxy-2-pyridones | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-10-06 | — | — | US | disclosed |
| EP-0710650-B1 | Process for the preparation of 1-hydroxy-2-pyridones | HOECHST AG (DE) | 1998-08-26 | — | — | EP | disclosed |
| US-5756749-A | Process for the preparation of 1-hydroxy-2-pyridones | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-05-26 | — | — | US | disclosed |
| CN-1161690-A | Substituted pyridines, their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-10-08 | — | — | CN | disclosed |
| EP-0710650-A2 | Process for the preparation of 1-hydroxy-2-pyridones | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203822-A1 | COMPOUNDS FOR TREATMENT OF TUMORS BEARING DEREGULATED MYC ONCOPROTEINS | MYC, MYCBP, BCOR | MAOA 3409/4885MAOB 2669/4885LTA4H 4677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.