Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 7/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 7/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 7/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 7/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATIC | P31939 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621405 | 0.83 | GRIA1 (0.41) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| Bicarbonate SCHEMBL8805354 | 0.81 | CDK2 (0.41) | GRIA1GRIA2GRIA3GRIA4CDK2 | |
| SCHEMBL3668211 | 0.79 | GRIK1 (0.59) | GRIA1GRIA2GRIA3GRIA4KMT2A | |
| SCHEMBL8619799 | 0.78 | CDK2 (0.38) | GRIA1GRIA2GRIA3GRIA4CDK2 | |
| SCHEMBL7482033 | 0.77 | FDPS (0.55) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8624851 | 0.77 | KMT2A (0.33) | GRIA1GRIA2GRIA3GRIA4CDK2 | |
| SCHEMBL8616696 | 0.73 | CDK2 (0.37) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8622149 | 0.72 | KMT2A (0.35) | GRIA1GRIA2GRIA3GRIA4GRIN2D | |
| SCHEMBL8617926 | 0.72 | CDK2 (0.35) | GRIA1GRIA2GRIA3GRIA4CDK2 | |
| SCHEMBL9747625 | 0.69 | KMT2A (0.56) | GRIA1GRIA2GRIA3GRIA4GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |