Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553019 | 0.75 | RXRA (0.46) | CA12CA1CA2CA9MAOA | |
| SCHEMBL8546261 | 0.72 | RXRA (0.53) | CA12CA1CA2CA9MAOA | |
| SCHEMBL8650315 | 0.67 | HDAC1 (0.43) | CA12CA1CA2CA9MAOA | |
| SCHEMBL8551221 | 0.64 | CA2 (0.51) | CA12CA1CA2CA9MAOA | |
| SCHEMBL8546263 | 0.62 | RXRA (0.50) | PTGS2PTGS1 | |
| SCHEMBL8474573 | 0.62 | CA1 (0.47) | CA12CA1CA2CA9MAOA | |
| SCHEMBL6307366 | 0.62 | PTGS1 (0.55) | CA12CA1CA2CA9MAOA | |
| SCHEMBL5761886 | 0.62 | CA2 (0.46) | CA12CA1CA2CA9S1PR1 | |
| SCHEMBL8548370 | 0.62 | RXRA (0.60) | PTGS2PTGS1KDM4E | |
| SCHEMBL5763086 | 0.61 | CA2 (0.47) | CA12CA1CA2CA9PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |