Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615723 | 0.75 | ACHE (0.59) | ACHEHTR2A | |
| SCHEMBL16495159 | 0.75 | ACHE (0.45) | ACHE | |
| SCHEMBL8613640 | 0.74 | NOTUM (0.52) | KDM4E | |
| SCHEMBL3392214 | 0.72 | CARM1 (0.63) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL118883 | 0.72 | HDAC1 (0.53) | ACHESLC22A12 | |
| SCHEMBL2001003 | 0.69 | ACHE (0.48) | ACHEHTR2AHTR2CSLC22A12 | |
| SCHEMBL18106575 | 0.69 | HDAC1 (0.53) | ACHEKDM4ESLC22A12 | |
| SCHEMBL16030871 | 0.69 | CYP1A2 (0.55) | ACHEHTR2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL8616710 | 0.69 | ACHE (0.48) | ACHESLC22A12 | |
| SCHEMBL15701646 | 0.69 | ADRB2 (0.47) | ACHEHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998050346-A2 | ACETAMIDE AND UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 1998-11-12 | — | — | WO | disclosed |