Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8617193 | 0.92 | GAA (0.39) | KMT2AL3MBTL1ALDH1A1TP53 | |
| SCHEMBL8617850 | 0.91 | S1PR5 (0.37) | L3MBTL1 | |
| SCHEMBL8613400 | 0.89 | GFER (0.41) | KMT2AMEN1PDE10AALDH1A1POLB | |
| SCHEMBL8614073 | 0.88 | S1PR5 (0.37) | L3MBTL1ALDH1A1 | |
| SCHEMBL8617986 | 0.88 | KDM4E (0.32) | KMT2AMEN1L3MBTL1PDE10AALDH1A1 | |
| SCHEMBL8620687 | 0.87 | PDE10A (0.45) | KMT2AMEN1PDE10AALDH1A1POLB | |
| SCHEMBL8620017 | 0.87 | DHODH (0.37) | KMT2AMEN1ALDH1A1TP53ADORA1 | |
| SCHEMBL8615146 | 0.87 | ALDH1A1 (0.41) | KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL8618902 | 0.87 | TACR3 (0.32) | KMT2AMEN1ADORA2AMAPT | |
| SCHEMBL8620384 | 0.86 | MCHR1 (0.36) | KMT2AMEN1L3MBTL1ALDH1A1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |