Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 10/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620017 | 0.93 | DHODH (0.37) | MCHR1DHODHADORA3ADORA1SLC6A2 | |
| SCHEMBL8617986 | 0.88 | KDM4E (0.32) | ADORA3ADORA1GABRG2GABRB3GABRA2 | |
| SCHEMBL8617403 | 0.86 | KMT2A (0.41) | ADORA1KMT2AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL8617193 | 0.85 | GAA (0.39) | SLC6A4KDM4EKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL8613400 | 0.85 | GFER (0.41) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL8617850 | 0.84 | S1PR5 (0.37) | SLC6A4L3MBTL1HPGD | |
| SCHEMBL8614870 | 0.84 | ACP1 (0.41) | ADORA3ADORA1KDM4EKMT2AMEN1 | |
| SCHEMBL8620190 | 0.83 | MEN1 (0.33) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL8615146 | 0.82 | ALDH1A1 (0.41) | SLC6A4KDM4EKMT2AL3MBTL1MEN1 | |
| SCHEMBL8618902 | 0.82 | TACR3 (0.32) | GABRG2GABRB3GABRA2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726254-B1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0726254-A1 | Quinoline-4-carbonylguanidine derivates, process for producing the same and pharmaceutical preparations containing the compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-08-14 | — | — | EP | disclosed |