Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.38 |
| ▸ | MAOB | P27338 | 8/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855938 | 0.81 | ALOX5 (0.39) | MAOAMAOBALOX5KCNJ1LMNA | |
| SCHEMBL855133 | 0.78 | KCNJ1 (0.44) | MAOAMAOBKCNJ1LMNAGAA | |
| SCHEMBL30365884 | 0.78 | KCNJ1 (0.44) | MAOAMAOBKCNJ1LMNAGAA | |
| SCHEMBL854099 | 0.77 | ALOX5 (0.39) | MAOAMAOBALOX5KCNJ1LMNA | |
| SCHEMBL15680228 | 0.76 | ALOX5 (0.36) | MAOAMAOBALOX5 | |
| SCHEMBL855171 | 0.76 | ALOX5 (0.36) | MAOAMAOBALOX5KCNJ1LMNA | |
| SCHEMBL855294 | 0.74 | MAOA (0.38) | MAOAMAOBALOX5KCNJ1LMNA | |
| SCHEMBL855545 | 0.73 | TGM2 (0.40) | MAOAMAOBALOX5KCNJ1LMNA | |
| SCHEMBL23496800 | 0.73 | MAPT (0.40) | MAOAMAOBALOX5KCNJ1LMNA | |
| SCHEMBL23513237 | 0.73 | KCNJ1 (0.42) | MAOAMAOBALOX5KCNJ1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433933-B1 | PRODUCTION METHOD OF TRI- OR TETRAHALOGEN-SUBSTITUTED PHTHALIDE | SUMITOMO CHEMICAL CO (JP) | 2019-05-08 | — | — | EP | disclosed |
| US-8604221-B2 | Production method of halogen-substituted phthalide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-12-10 | — | — | US | disclosed |
| US-20120142946-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-07 | — | — | US | disclosed |
| EP-2433933-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | Sumitomo Chemical Company, Limited (JP) | 2012-03-28 | — | — | EP | disclosed |