Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.39 |
| ▸ | MAOA | P21397 | 5/20 | 0.36 |
| ▸ | MAOB | P27338 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL861759 | 0.77 | MAOA (0.38) | ALOX5MAOAMAOBLMNAGAA | |
| SCHEMBL855513 | 0.76 | KCNJ1 (0.46) | ALOX5MAOAMAOBLMNAGAA | |
| SCHEMBL855545 | 0.76 | TGM2 (0.40) | ALOX5MAOAMAOBLMNAGAA | |
| SCHEMBL855171 | 0.76 | ALOX5 (0.36) | ALOX5MAOAMAOBLMNAGAA | |
| SCHEMBL20811853 | 0.73 | KCNJ1 (0.40) | ALOX5MAOAMAOBLMNAKCNJ1 | |
| SCHEMBL855628 | 0.72 | NUAK1 (0.35) | ALOX5GAAALDH1A1 | |
| SCHEMBL854481 | 0.71 | CYP3A4 (0.53) | MAOAMAOBLMNAGAAMAPT | |
| SCHEMBL3873999 | 0.71 | MAOA (0.41) | ALOX5MAOAMAOB | |
| SCHEMBL856025 | 0.69 | MAOB (0.47) | ALOX5MAOAMAOBLMNAGAA | |
| SCHEMBL26112753 | 0.69 | LMNA (0.41) | ALOX5MAOAMAOBLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433933-B1 | PRODUCTION METHOD OF TRI- OR TETRAHALOGEN-SUBSTITUTED PHTHALIDE | SUMITOMO CHEMICAL CO (JP) | 2019-05-08 | — | — | EP | disclosed |
| CN-105849094-A | Method for producing halogen-substituted phthalide | 住友化学株式会社 | 2016-08-10 | — | — | CN | disclosed |
| US-8604221-B2 | Production method of halogen-substituted phthalide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-12-10 | — | — | US | disclosed |
| US-20120142946-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-07 | — | — | US | disclosed |
| EP-2433933-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | Sumitomo Chemical Company, Limited (JP) | 2012-03-28 | — | — | EP | disclosed |