Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621279 | 0.79 | ALDH1A1 (0.36) | ALDH1A1HPRT1TSHRTDP1MEN1 | |
| SCHEMBL8620563 | 0.78 | HSP90AA1 (0.50) | ALDH1A1HPRT1TSHRMEN1KMT2A | |
| SCHEMBL8620590 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HPRT1TSHRTDP1MEN1 | |
| SCHEMBL7358348 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HPRT1TSHRTDP1MEN1 | |
| SCHEMBL29094639 | 0.76 | ALDH1A1 (0.55) | ALDH1A1HPRT1TSHRTDP1MEN1 | |
| SCHEMBL6171290 | 0.75 | MAPT (0.38) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL8907167 | 0.73 | ALDH1A1 (0.55) | ALDH1A1HPRT1TSHRTDP1MEN1 | |
| SCHEMBL21647267 | 0.72 | HPRT1 (0.37) | ALDH1A1HPRT1TSHRTDP1MEN1 | |
| SCHEMBL27352431 | 0.71 | ALDH1A1 (0.49) | ALDH1A1HPRT1TSHRTDP1MEN1 | |
| SCHEMBL11619937 | 0.71 | ALDH1A1 (0.53) | ALDH1A1HPRT1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1041935-C | Benzo[f]quinoxalindione derivatives, their preparation and their use in drugs | SCHERING AG (DE) | 1999-02-03 | — | — | CN | disclosed |
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| EP-0696289-B1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1997-03-12 | — | — | EP | disclosed |
| CN-1122136-A | Benzo[f]quinoxalindione derivatives, their preparation and their use in drugs | SCHERING AG (DE) | 1996-05-08 | — | — | CN | disclosed |
| EP-0696289-A1 | BENZO F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025470-A1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-11-10 | — | — | WO | disclosed |